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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rfhealth</journal-id><journal-title-group><journal-title xml:lang="ru">Здравоохранение Российской Федерации</journal-title><trans-title-group xml:lang="en"><trans-title>Health care of the Russian Federation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0044-197X</issn><issn pub-type="epub">2412-0723</issn><publisher><publisher-name>Federal Scientific Center of Hygiene named after F.F. Erisman</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47470/0044-197X-2023-67-2-118-122</article-id><article-id custom-type="edn" pub-id-type="custom">ktlbob</article-id><article-id custom-type="elpub" pub-id-type="custom">rfhealth-1178</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРГАНИЗАЦИЯ ЗДРАВООХРАНЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>HEALTH CARE ORGANIZATION</subject></subj-group></article-categories><title-group><article-title>Причины смертельных исходов жителей г. Алматы до и в период пандемии COVID-19</article-title><trans-title-group xml:lang="en"><trans-title>Causes of death in Almaty residents before and during the COVID-19 pandemic</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4105-4008</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Камхен</surname><given-names>Виталий Брониславович</given-names></name><name name-style="western" xml:lang="en"><surname>Kamkhen</surname><given-names>Vitaly B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>И.о. доцента каф. эпидемиологии, биостатистики и доказательной медицины, Казахский национальный университет имени аль-Фараби, 050040, г. Алматы, Казахстан.</p><p>e-mail: kamchen.v.b@gmail.com</p></bio><bio xml:lang="en"><p>Acting Associate Professor of the Department of Epidemiology, Biostatistics and Evidence-Based Medicine, Al-Farabi Kazakh National University, Almaty, 050040, Republic of Kazakhstan.</p><p>e-mail: kamchen.v.b@gmail.com</p></bio><email xlink:type="simple">kamchen.v.b@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3840-4284</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мамырбекова</surname><given-names>Салтанат А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mamyrbekova</surname><given-names>Saltanat A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4402-5093</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Идаят</surname><given-names>Малика Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Idayat</surname><given-names>Malika G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Казахский национальный университет имени аль-Фараби</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Al-Farabi Kazakh National University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2023</year></pub-date><volume>67</volume><issue>2</issue><fpage>118</fpage><lpage>122</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Камхен В.Б., Мамырбекова С.А., Идаят М.Г., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Камхен В.Б., Мамырбекова С.А., Идаят М.Г.</copyright-holder><copyright-holder xml:lang="en">Kamkhen V.B., Mamyrbekova S.A., Idayat M.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.rfhealth.ru/jour/article/view/1178">https://www.rfhealth.ru/jour/article/view/1178</self-uri><abstract><sec><title>Введение</title><p>Введение. В период пандемии COVID-19 возможно изменение основных причин смерти в популяции за счёт как инфекционной заболеваемости, так и сопутствующей хронической патологии, ассоциированной с коронавирусной инфекцией.</p><p>Цель исследования — изучение особенности структуры и динамики смертельных исходов среди жителей Алматы в контексте пандемии COVID-19.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. Материалом для анализа послужили регистровые данные о случаях смертельных исходов среди жителей г. Алматы Республики Казахстан за 2018–2020 гг. Изучались структура и динамика смертельных исходов по полу и возрасту в зависимости от даты и места смерти и с учётом класса заболеваний.</p></sec><sec><title>Результаты</title><p>Результаты. В 2020 г. количество смертельных исходов в Алматы увеличилось в 1,37 и 1,40 раза в сравнении с 2018 и 2019 гг. Выявлены различия в случаях смерти по полу и возрасту. В динамике существенно увеличилось количество смертельных исходов, регистрированных в стационаре, и уменьшилось количество летальных исходов на дому. В 2020 г. в структуре причин смерти преобладали 5 основных классов заболеваний: I00–I99, G00–G99, C00–D48, J00–J99, U07.1–U07.2.</p></sec><sec><title>Ограничения исследования</title><p>Ограничения исследования. Для анализа предмета исследования использованы все случаи смертельных исходов, регистрированные в Алматы, что увеличивает достоверность статистических выводов.</p></sec><sec><title>Заключение</title><p>Заключение. Во время пандемии COVID-19, в сравнении с предыдущими годами, изменилась структура причин смерти среди жителей Алматы. Отмечается прирост случаев смерти, который обусловлен, прежде всего, коронавирусной инфекцией и заболеваниями, ассоциированными с ней. Возможен недоучёт случаев смерти по причине COVID-19 среди жителей Алматы вследствие ошибочной регистрации коморбидных заболеваний.</p><p>Соблюдение этических стандартов. В настоящем исследовании использовались регистровые данные о случаях смертельных исходов без идентификации объектов наблюдения.</p></sec><sec><title>Участие авторов</title><p>Участие авторов: Камхен В.Б. — концепция проекта, статистическая обработка материала, интерпретация и обсуждение полученных результатов, представление основных результатов; Мамырбекова С.А. — концепция проекта, обоснование актуальности исследования, работа с литературными источниками, редактирование статьи; Идаят М.Г. — концепция проекта, резюмирование результатов, окончательное редактирование статьи и перевод фрагмента рукописи на английский язык. Все соавторы — утверждение окончательного варианта статьи, ответственность за целостность всех частей статьи.</p></sec><sec><title>Финансирование</title><p>Финансирование. Исследование не имело спонсорской поддержки. </p></sec><sec><title>Конфликт интересов</title><p>Конфликт интересов. Авторы декларируют отсутствие явных и потенциальных конфликтов интересов в связи с публикацией данной статьи.</p></sec><sec><title>Поступила 13</title><p>Поступила 13.03.2022Принята в печать 12.05.2022Опубликована 28.04.2023 </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. It was conducted a study of the structure and dynamics of death outcomes among Almaty residents over the COVID-19 pandemic. The leading causes of death in the population during this period may change, both through infectious morbidity and losses due to concomitant chronic non-communicable diseases associated with coronavirus infection.</p></sec><sec><title>Material and methods</title><p>Material and methods. The material for the analysis was the registered data on case of deaths among Almaty residents in Kazakhstan between 2018 and 2020. We studied the structure and trend in cases of death by gender and age of patients, depending on the date and place of death and in view of the class of diseases.</p></sec><sec><title>Results</title><p>Results. During 2020, the number of deaths of Almaty residents increased in 1.37 and 1.40 times compared to 2018 and 2019. Differences in deaths on gender and age of patients were revealed. In trend, the number of deaths recorded in the hospital has significantly increased whereas the number of deaths at home has decreased. In 2020, five major classes of diseases dominated in the structure of causes of death: 1) I00-I99, 2) G00-G99, 3) C00-D48, 4) J00-J99, and 5) U07.1 and U07.2.</p></sec><sec><title>Research limitations</title><p>Research limitations. All cases of deaths registered in Almaty were used to analyse the subject of the study, which increases the reliability of statistical conclusions.</p></sec><sec><title>Conclusion</title><p>Conclusion. During the COVID-19 pandemic the structure of causes of death among residents of Almaty changed when compared with previous years. There was gain in deaths, which is primarily due to coronavirus infection and diseases associated with COVID-19. It is possible underreporting of deaths from COVID-19 among residents of Almaty which related with false registration of comorbid diseases.</p><p>Compliance with ethical standards. In this study, we used register data on cases of deaths without identifying the objects of observation.</p><p>Contribution of the authors: Kamkhen V.B. — the concept of the project, statistical processing of the material, interpretation, and discussion of the results obtained, presentation of the main results; Mamyrbekova S.A. — the concept of the project, justification of the relevance of the study, work with literary sources, editing the article; Idayat M.G. — the concept of the project, summarizing the results, final editing of the article and translation of the manuscript fragment into English. All co-authors — approval of the final version of the article, responsibility for the integrity of all parts of the article.</p></sec><sec><title>Acknowledgment</title><p>Acknowledgment. The study had no sponsorship.</p></sec><sec><title>Conflict of interest</title><p>Conflict of interest. The authors declare no conflict of interest. </p></sec><sec><title>Received</title><p>Received: March 13, 2022Accepted: May 12, 2022Published: April 28, 2023</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>смертельные исходы</kwd><kwd>коморбидные заболевания</kwd><kwd>пандемия COVID-19</kwd><kwd>Алматы</kwd><kwd>Казахстан</kwd></kwd-group><kwd-group xml:lang="en"><kwd>deaths</kwd><kwd>comorbid diseases</kwd><kwd>COVID-19 pandemic</kwd><kwd>Almaty</kwd><kwd>Kazakhstan</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rampatige R., Mikkelsen L., Hernandez B., Riley I., Lopez A.D. Systematic review of statistics on causes of deaths in hospitals: strengthening the evidence for policy-makers. Bull. 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